3-Isomangostin

• Target:

  MTH1|||DNA/RNA Synthesis

• Related Pathways:

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

• Purity:

  0.999

• Bioactivity:

  3-Isomangostin is an acetylcholinesterase selective inhibitor and a potent human aldose reductase inhibitor with an IC50 of 3.48 uM. 3-Isomangostin has free radical scavenging activity and inhibits MutT homolog 1 (MTH1) with an IC50 of 52 nM. It shows antiplasmodial activity with an IC50 values in the range of 4.71-11.40 uM. 3-Isomangostin can be used to develop anticancer agents as well.

• Smiles:

  COc1c (O) cc2oc3cc4OC (C) (C) CCc4c (O) c3c (=O) c2c1CC=C (C) C

• Molecular Formula:

  C24H26O6

• Molecular Weight:

  410.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  19275-46-8