3-Isomangostin

CAT: 0931-MF-0017128-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0017128-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
19275-46-8
Target
MTH1|||DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair|||Cell Cycle/Checkpoint
Purity
0.999
Bioactivity
3-Isomangostin is an acetylcholinesterase selective inhibitor and a potent human aldose reductase inhibitor with an IC50 of 3.48 uM. 3-Isomangostin has free radical scavenging activity and inhibits MutT homolog 1 (MTH1) with an IC50 of 52 nM. It shows antiplasmodial activity with an IC50 values in the range of 4.71-11.40 uM. 3-Isomangostin can be used to develop anticancer agents as well.
Smiles
COc1c(O)cc2oc3cc4OC(C)(C)CCc4c(O)c3c(=O)c2c1CC=C(C)C
Molecular Formula
C24H26O6
Molecular Weight
410.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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