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Daurinoline

CAT: 0931-T2S0118-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T2S0118-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2831-75-6
Target
Histamine Receptor, Calcium Channel, 5-HT Receptor
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Membrane transporter/Ion channel, Metabolism, Neuroscience
Bioactivity
Daurinoline is a non-competitive antagonist, it exerts marked relaxation effect on basilar artery of rabbits through non-competitive antagonism, it would have a protective function on microcirculation of cerebral pia mater, which may be beneficial to relieve cerebral ischemic injury. Daurinoline could significantly reverse noradrenaline induced constriction of pial arterioles and venules, and increase the number of blood vessels which were decreased by noradrenaline.
Smiles
C([C@@H]1C=2C(=CC(OC)=C(OC)C2)CCN1C)C3=CC(OC4=CC=C(C[C@@H]5C=6C(=CC(O)=C(OC)C6)CCN5C)C=C4)=C(O)C=C3
Molecular Formula
C37H42N2O6
Molecular Weight
610.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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