ABT-770

CAT: 0931-T29532-02Size: 50 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T29532-02Size:50 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

220614-50-6

Target

Others, MMP

Related Pathways

Proteases/Proteasome, Others

Bioactivity

ABT-770 is an MMP inhibitor, a potent, selective, and orally bioavailable compound. It has been shown to significantly inhibit tumor growth in animal cancer models.

Smiles

O(C(F)(F)F)C1=CC=C(C=C1)C2=CC=C(OC[C@H](CN3C(=O)C(C)(C)NC3=O)N(C=O)O)C=C2

Molecular Formula

C22H22F3N3O6

Molecular Weight

481.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Abt-770

structure in first source

CAS Number	220614-50-6
PubChem CID	9869811
IUPAC Name	N-[(2S)-1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-3-[4-[4-(trifluoromethoxy)phenyl]phenoxy]propan-2-yl]-N-hydroxyformamide
Molecular Formula	C22H22F3N3O6
Molecular Weight	481.4
XLogP	3.3
Topological Polar Surface Area	108
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	8
Heavy Atom Count	34
Formal Charge	0
Complexity	734

SMILES

CC1(C(=O)N(C(=O)N1)C[C@@H](COC2=CC=C(C=C2)C3=CC=C(C=C3)OC(F)(F)F)N(C=O)O)C

InChI

InChI=1S/C22H22F3N3O6/c1-21(2)19(30)27(20(31)26-21)11-16(28(32)13-29)12-33-17-7-3-14(4-8-17)15-5-9-18(10-6-15)34-22(23,24)25/h3-10,13,16,32H,11-12H2,1-2H3,(H,26,31)/t16-/m0/s1

InChIKey

IIHFBHZWJNGWRC-INIZCTEOSA-N

Chemical Structure

2D Structure

CAS: 220614-50-6

CID: 9869811

Formula: C22H22F3N3O6

MW: 481.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	481.4
XLogP3	3.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	8
Exact Mass	481.14606992
Monoisotopic Mass	481.14606992
Topological Polar Surface Area	108 Å²
Heavy Atom Count	34
Formal Charge	0
Complexity	734
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
TQ0241-01	TUG-770
T11150-01	Ecteinascidin 770
T40951-01	ABT-107
T69503-01	ABT-518
T4668L-01	ABT-702
T14085	ABT-046
T29527-01	ABT-255
T29523-01	ABT 29666
T26524-01	ABT-080
T29525-01	ABT-116

Alternative Products

Catalog	Name
MBS5779166	ABT-770
A3895-25	TUG-770
TRC-E225900-1MG	Ecteinascidin 770
MBS8506210-01	VX-770
AR-T05239-01	Tinuvin 770

ABT-770

Chemical Information

Related Products

Alternative Products

Popular Products