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Upacicalcet

CAT: 0931-T29067-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T29067-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1333218-50-0
Target
Calcium Channel|||CaSR
Related Pathways
GPCR/G Protein|||Metabolism|||Membrane transporter/Ion channel
Purity
0.9988
Bioactivity
Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-sensitive receptors, thereby lowering blood levels of PTH.Upacicalcet is an orthosteric modulator of calcium-sensitive receptors and prevents adenine-induced secondary vascular calcification and bone disease in a rat model of adenine-induced secondary hyperparathyroidism.
Smiles
N(C(NC[C@@H](C(O)=O)N)=O)C1=CC(S(=O)(=O)O)=CC(Cl)=C1C
Molecular Formula
C11H14ClN3O6S
Molecular Weight
351.76
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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