T-1095A

• Target :

  Others|||Drug Metabolite

• Related Pathways :

  Metabolism|||Others

• Bioactivity :

  T-1095A is an active metabolite of T-1095, a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs) . Chronic administration of T-1095 (0.1% w w (-1) pellet chow, for 12 weeks) decreased blood glucose and haemoglobin A (1C) levels, and improved glucose intolerance in db/db mice. Long-term treatment with T-1095 causes sustained improvement in hyperglycemia and prevents diabetic neuropathy in Goto-Kakizaki Rats.

• Smiles :

  C(CCC=1C=C2C(=CC1)OC=C2)(=O)C3=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=C(C)C=C3O

• Molecular Formula :

  C24H26O9

• Molecular Weight :

  458.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  209746-56-5