PHPS1

• Target :

  Phosphatase

• Related Pathways :

  Metabolism

• Purity :

  0.9977

• Bioactivity :

  PHPS1 is an inhibitor of Shp2. PHPS1 efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines.

• Smiles :

  OS(=O)(=O)c1ccc(N\N=C2/C(=O)N(N=C2c2ccc(cc2)[N+]([O-])=O)c2ccccc2)cc1

• Molecular Formula :

  C21H15N5O6S

• Molecular Weight :

  465.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  314291-83-3