NEU-1045

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  NEU-1045 is a T. brucei proliferation inhibitor, and is a promising lead with cross-pathogen activity. NEU-1045 inhibited T. brucei, T. cruzi, and L. major proliferation with good potency (T. brucei EC50 = 0.37 ?M; T. cruzi EC50 = 2.8 ?M; L. major EC50 = 1.2 ?M) .

• Smiles:

  FC1=CC(COC(C=C2)=CC=C2NC3=CC=NC(C3=C4)=CC=C4C5=CC=C(S(N6CCOCC6)(=O)=O)C=C5)=CC=C1

• Molecular Formula:

  C32H28FN3O4S

• Molecular Weight:

  569.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C