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NCG21

CAT: 0931-T28140-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T28140-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1079821-35-4
Target
Others, GPCR
Related Pathways
Others, GPCR/G Protein, Endocrinology/Hormones
Bioactivity
NCG21 is a GPR120 agonist, which showed potent extracellular signal-regulated kinase (ERK) activation in a cloned GPR120 system. NCG21 potently activated ERK, intracellular calcium responses and GLP-1 secretion in murine enteroendocrine STC-1 cells that express GPR120 endogenously. Administration of NCG21 into the mouse colon caused an increase in plasma GLP-1 levels.
Smiles
O=C(O)CCCC1=CC=C(OCCN(C2=NC=CC=C2)C=3C=CC=CC3)C=C1
Molecular Formula
C23H24N2O3
Molecular Weight
376.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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