MLN-3897

• Target :

  CCR

• Related Pathways :

  Microbiology/Virology|||Immunology/Inflammation|||GPCR/G Protein

• Purity :

  0.9862

• Bioactivity :

  MLN-3897 (CCR1 antagonist 10) is an orally active antagonist of CCR1 with a Ki of 2.3 nM for 125I-MIP-1? binding to THP-1 cell membranes. MLN-3897 inhibits Akt signaling and MM cell survival and proliferation.

• Smiles :

  C(CCN1CC(C)(C)[C@](O)(CC1)C2=CC=C(Cl)C=C2)=C3C=4C(OCC=5C3=CC=CN5)=CC=C(C(O)=O)C4

• Molecular Formula :

  C30H31ClN2O4

• Molecular Weight :

  519.03

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1010731-97-1