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LSN2814617

CAT: 0931-T27855-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T27855-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1313498-17-7
Target
Others, GluR
Related Pathways
Others, Neuroscience
Bioactivity
LSN2814617 is an orally active, potent, brain-penetrant, and selective mGlu 5 (metabotropic glutamate 5) positive allosteric modulator (PAM), with EC 50 values of 52 nM (Human mGlu5) and 42 nM (rat mGlu5) . In vivo EEG studies demonstrated that LSN2463359 has marked wake-promoting properties with minimal rebound hypersomnolence, and it can be used for schizophrenia research [1].
Smiles
C(C)(C)(C)C=1N2C(C[C@H](CC2)C3=NC(=NO3)C4=CC=C(F)C=C4)=NN1
Molecular Formula
C18H20FN5O
Molecular Weight
341.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C