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KYA1797

CAT: 0931-T27760-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T27760-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
851304-36-4
Target
Others, Kras, Ras
Related Pathways
MAPK, Others
Bioactivity
KYA1797 is an inhibitor of the Wnt/ß-catenin pathway. KYA1797 binds directly to the regulators of G-protein signaling domain of axin, initiats ß-catenin and Ras degradation through enhancement of the ß-catenin destruction complex activating GSK3ß, effectively suppresses the growth of CRCs harboring APC and KRAS mutations.
Smiles
OC(=O)CCN1C(=S)S\C(=C/C2=CC=C(O2)C2=CC=C(C=C2)[N+]([O-])=O)C1=O
Molecular Formula
C17H12N2O6S2
Molecular Weight
404.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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GTR19197331-01KYA1797

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