Products for Research Use Only
RegisterLogin

KT109

CAT: 0931-T27752-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T27752-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1402612-55-8
Target
Others, MAGL
Related Pathways
Metabolism, Others
Bioactivity
KT109 is a selective inhibitor of DAGLβ (IC50 = 42 nM) . KT109-treated wild-type mice displayed reductions in LPS-induced allodyni as well as in DAGL-β (-/-) micea. Repeated KT109 administration prevented the expression of LPS-induced allodynia, without evidence of tolerance. Intraplantar injection of KT109 into the LPS-treated paw, but not the contralateral paw, reversed the allodynic responses. KT109 also reversed allodynia in the CCI and CINP models and lacked discernible side effects (e.g. anxiogenic behaviour, gross motor deficits or gastric ulcers) .
Smiles
O=C(N1CCCCC1Cc1ccccc1)n1cc(nn1)-c1ccc(cc1)-c1ccccc1
Molecular Formula
C27H26N4O
Molecular Weight
422.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
453073-01KT109
GTR19190249-01(R) -KT109
HY-126031A(S) -KT109
MBS5798783(R)-KT109
MBS5798882(S)-KT109
GTR19232292-01KT109 N2 Regioisomer

Popular Products