GX-936

• Target:

  Sodium Channel

• Related Pathways:

  Membrane transporter/Ion channel

• Bioactivity:

  GX-936 (PF-05196233) is a selective Nav1.7 inhibitor that binds to the activated state of VSD4 (voltage-sensor domain IV), thereby opposing VSD4 inactivation and inhibiting Nav1.7. It can be used for pain perception research.

• Smiles:

  N#CC1=CC(=CC=C1OC=2C=CC(=CC2C3=CC=NN3C4CN(CC)C4)C(F)(F)F)S(=O)(=O)NC5=NC=NS5

• Molecular Formula:

  C24H20F3N7O3S2

• Molecular Weight:

  575.59

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1235406-09-3