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GSK1733953A

CAT: 0931-T27453-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T27453-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
930470-97-6
Target
Antibacterial
Related Pathways
Microbiology/Virology
Purity
0.9994
Bioactivity
GSK1733953A can be used as a small molecule Mycobacterium tuberculosis respiration inhibitor with an inhibitory effect on MenG activity and an IC50 value of 2.6 ± 0.6 μM.GSK1733953A is a selective biphenylbenzamide with an inhibitory effect on the catalytic methylation of the Mycobacterium tuberculosis desmethylnaphthoquinone methyltransferase, and the MIC of GSK1733953A against Mycobacterium tuberculosis H4Rv was 8.37 μg/ml. MIC of 8.37 μg/ml and MIC of 1.2 to 9.6 μg/ml against drug-resistant strains.GSK1733953A is a candidate compound for the treatment of tuberculosis.
Smiles
O(C)C1=C(C=C(NC(=O)C2=C(Cl)C=C(F)C=C2)C=C1)C3=CC=C(OC)C=C3
Molecular Formula
C21H17ClFNO3
Molecular Weight
385.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19198157-01GSK1733953A

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