FR-167356

CAT: 0931-T27371-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T27371-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

174185-16-1

Target

ATPase, Proton pump

Related Pathways

Membrane transporter/Ion channel

Purity

0.9974

Bioactivity

FR-167356 is a specific inhibitor of a3 isoform vacuolar type H+-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush border membranes and macrophage microsomes. FR-167356 reduces bone metastasis of B16-F10 cells.

Smiles

C(C)(C)(O)C=1C=2C(=C(NC(=O)C3=C(Cl)C=CC=C3Cl)C=CC2)OC1C

Molecular Formula

C19H17Cl2NO3

Molecular Weight

378.25

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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