FR-167356

• Target :

  ATPase|||Proton pump

• Related Pathways :

  Membrane transporter/Ion channel

• Purity :

  0.9974

• Bioactivity :

  FR-167356 is a specific inhibitor of a3 isoform vacuolar type H?-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush border membranes and macrophage microsomes. FR-167356 reduces bone metastasis of B16-F10 cells.

• Smiles :

  C(C)(C)(O)C=1C=2C(=C(NC(=O)C3=C(Cl)C=CC=C3Cl)C=CC2)OC1C

• Molecular Formula :

  C19H17Cl2NO3

• Molecular Weight :

  378.25

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  174185-16-1