DA-6886

• Target :

  5-HT Receptor

• Related Pathways :

  GPCR/G Protein|||Neuroscience

• Purity :

  0.9999

• Bioactivity :

  DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4) . DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels revealed that it inhibited hERG channel current with an pIC50 value of 4.3, indicating that the compound was 1000-fold more selective for the 5-HT4 receptor over hERG channels.

• Smiles :

  Cl.O=C(NCC1CCN(CCCN2N=NC=C2)CC1)C3=CC(Cl)=C(N)C=C3OC

• Molecular Formula :

  C19H28Cl2N6O2

• Molecular Weight :

  443.37

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1645260-76-9