DA-6886

CAT: 0931-MF-0046265-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0046265-01Size:1 mg
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CAS Number
1645260-76-9
Target
5-HT Receptor
Related Pathways
GPCR/G Protein|||Neuroscience
Purity
0.9999
Bioactivity
DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4) . DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels revealed that it inhibited hERG channel current with an pIC50 value of 4.3, indicating that the compound was 1000-fold more selective for the 5-HT4 receptor over hERG channels.
Smiles
Cl.O=C(NCC1CCN(CCCN2N=NC=C2)CC1)C3=CC(Cl)=C(N)C=C3OC
Molecular Formula
C19H28Cl2N6O2
Molecular Weight
443.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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