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Butaprost

CAT: 0931-T26925-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0931-T26925-01Size:500 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
69685-22-9
Target
TGF-beta/Smad, Others, Prostaglandin Receptor
Related Pathways
Immunology/Inflammation, Others, Stem Cells, GPCR/G Protein
Bioactivity
Butaprost is a chemical compound that functions as a selective agonist for the prostaglandin E receptor (EP2) . It exhibits an EC50 of 33 nM and a Ki of 2.4 μM when interacting with the murine EP2 receptor. However, Butaprost demonstrates lower activity against murine EP1, EP3, and EP4 receptors. Furthermore, it effectively attenuates fibrosis by inhibiting the TGF-β/Smad2 signaling pathway [1] [2] [3].
Smiles
[C@@H](C/C=C/[C@@H]1[C@@H](CCCCCCC(OC)=O)C(=O)C[C@H]1O)(O)C2(CCC)CCC2
Molecular Formula
C24H40O5
Molecular Weight
408.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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