Bencycloquidium Bromide

• Target :

  Others|||AChR

• Related Pathways :

  Neuroscience|||Others

• Bioactivity :

  Bencycloquidium Bromide is a muscarinic M3 antagonist. Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis. Bencycloquidium Bromide showed high affinity toward the M (3) receptor in Chinese hamster ovary (CHO) cells (M (1) pKi=7.86, M (2) pKi=7.21, M (3) pKi=8.21) ; pA (2) =8.85, 8.71 and 8.57 in methacholine-induced contraction of trachea, ileum and urinary bladder, 8.19 in methacholine-induced bradycardia of right atrium in vitro, respectively.This compound is unstable in powder form and other related salt forms are recommended.

• Smiles :

  [Br-].OC(C=1C=CC=CC1)(COC2C[N+]3(C)CCC2CC3)C4CCCC4

• Molecular Formula :

  C21H32BrNO2

• Molecular Weight :

  410.39

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  860804-18-8