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Azadirone

CAT: 0931-T26709-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T26709-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
30002-86-9
Target
TNF, Bcl-2 Family, Parasite, Others
Related Pathways
Apoptosis, Microbiology/Virology, Others
Bioactivity
Azadirone is a limonoid tetranortriterpene. Azadirone can sensitize cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through ROS-ERK-CHOP-mediated up-regulation of DR4 and DR5 signaling, down-regulation of cell survival proteins, and up-regulation of proapoptotic proteins.
Smiles
[H][C@@]12CO[C@@H](CN(N=O)C(N)=O)[C@]1([H])OC(C)(C)O2
Molecular Formula
C9H15N3O5
Molecular Weight
245.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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