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PD173074

CAT: 0931-T2642-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T2642-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
219580-11-7
Target
FGFR, EGFR, Apoptosis, VEGFR, IGF-1R, Src
Related Pathways
Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Purity
0.9821
Bioactivity
PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.
Smiles
CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1cc(OC)cc(OC)c1
Molecular Formula
C28H41N7O3
Molecular Weight
523.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C