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Triparanol

CAT: 0931-T26296-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T26296-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
78-41-1
Target
Hedgehog/Smoothened, Apoptosis
Related Pathways
Stem Cells, GPCR/G Protein, Apoptosis
Purity
0.9973
Bioactivity
Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparanol suppresses human tumor growth and is an antilipemic agent with high ophthalmic toxicity.
Smiles
C(CC1=CC=C(Cl)C=C1)(O)(C2=CC=C(OCCN(CC)CC)C=C2)C3=CC=C(C)C=C3
Molecular Formula
C27H32ClNO2
Molecular Weight
438
Shipping Conditions
Ice Packs
Storage Temperature
-20°C