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Vismodegib

CAT: 0931-T2590-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T2590-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
879085-55-9
Target
ABC Transporter, Autophagy, Hedgehog/Smoothened
Related Pathways
GPCR/G Protein, Membrane transporter/Ion channel, Stem Cells, Autophagy
Purity
0.9999
Bioactivity
Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM) . It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM) .
Smiles
ClC=1C(=CC(NC(=O)C2=C(Cl)C=C(S(C)(=O)=O)C=C2)=CC1)C3=CC=CC=N3
Molecular Formula
C19H14Cl2N2O3S
Molecular Weight
421.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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