Cabozantinib

• Target :

  C-Kit|||TAM Receptor|||VEGFR|||Apoptosis|||c-RET|||FLT|||c-Met/HGFR

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Apoptosis|||Angiogenesis

• Purity :

  0.9988

• Bioactivity :

  Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM) . Cabozantinib exhibits both antitumor and antiangiogenic activity.

• Smiles :

  C(NC1=CC=C(OC=2C3=C(C=C(OC)C(OC)=C3)N=CC2)C=C1)(=O)C4(C(NC5=CC=C(F)C=C5)=O)CC4

• Molecular Formula :

  C28H24FN3O5

• Molecular Weight :

  501.51

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  849217-68-1