NC190 sodium

CAT: 0931-T25857-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T25857-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

120602-99-5

Target

Others, Topoisomerase

Related Pathways

DNA Damage/DNA Repair, Others

Bioactivity

NC190 is an inhibitor of topoisomerase II that inhibited the growth of FM3A cells in clinical trials. NC-190 strongly inhibited the growth of FM3A cells when cultured with NC-190 for 48 h (IC50: 0.019 μg/ml) . NC-190 potently suppressed DNA synthesis with 90% inhibition observed at 0.1 μg/ml of NC-190.

Smiles

[Na].COc1cc2nc3c4ccccc4c(O)c(C(=O)NCCN(C)C)c3nc2cc1C(O)=O

Molecular Formula

C23H22N4NaO5

Molecular Weight

457.442

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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NC190 sodium

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