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NC1153

CAT: 0931-T25855-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T25855-02Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
150661-91-9
Target
Others, Endogenous Metabolite
Related Pathways
Metabolism, Others
Bioactivity
NC1153 is a blocker of IL-2-induced activation of JAK3 and its downstream substrates STAT5a/b. It promotes long-term allograft survival and sparing the recipient from multiple toxicities.
Smiles
Cl.Cl.CN(C)CC1CCCCCCCCCC(CN(C)C)C1=O
Molecular Formula
C18H38Cl2N2O
Molecular Weight
369.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

NC1153

a Jnk3 inhibitor; no further information available 9/2005

CAS Number150661-91-9
PubChem CID373395
IUPAC Name2,12-bis[(dimethylamino)methyl]cyclododecan-1-one
Molecular FormulaC18H36N2O
Molecular Weight296.5
XLogP4.3
Topological Polar Surface Area23.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Heavy Atom Count21
Formal Charge0
Complexity263
SMILES
CN(C)CC1CCCCCCCCCC(C1=O)CN(C)C
InChI
InChI=1S/C18H36N2O/c1-19(2)14-16-12-10-8-6-5-7-9-11-13-17(18(16)21)15-20(3)4/h16-17H,5-15H2,1-4H3
InChIKey
HRQRILLGGNNYSD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of NC1153
CAS: 150661-91-9
CID: 373395
Formula: C18H36N2O
MW: 296.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight296.5
XLogP34.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass296.282763776
Monoisotopic Mass296.282763776
Topological Polar Surface Area23.6 Ų
Heavy Atom Count21
Formal Charge0
Complexity263
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
GTR19198834-01NC1153

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