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Cilastatin

CAT: 0931-T2583-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T2583-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
82009-34-5
Target
Proteasome, Antibiotic, Antibacterial
Related Pathways
Proteases/Proteasome, Ubiquitination, Microbiology/Virology
Purity
0.9971
Bioactivity
Cilastatin (MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.
Smiles
CC1(C)C[C@@H]1C(=O)N\C(=C/CCCCSC[C@H](N)C(O)=O)C(O)=O
Molecular Formula
C16H26N2O5S
Molecular Weight
358.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
006831-01Cilastatin
C279-100MGCilastatin Sodium
ABDIC1010AImipenem/Cilastatin

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