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IDO5L

CAT: 0804-HY-15683-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15683-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IDO5L is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 67 nM.
CAS Number
914471-09-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/IDO5L.html
Purity
99.89
Solubility
DMSO : ≥ 52 mg/mL
Smiles
ON/C(C1=NON=C1N)=N/C2=CC=C(F)C(Cl)=C2
Molecular Formula
C9H7ClFN5O2
Molecular Weight
271.64
Precautions
H302, H315, H319, H335
References & Citations
[1]Yue EW, et al. Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model. J Med Chem. 2009 Dec 10;52 (23) :7364-7.|[2]Huang X, et al. Synthesis of [ (18) F] 4-amino-N- (3-chloro-4-fluorophenyl) -N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide (IDO5L) : a novel potential PET probe for imaging of IDO1 expression. J Labelled Comp Radiopharm. 2015 Apr;58 (4) :156-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO

Alternative Products

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BUP13634-01IDO5L
A13004-100IDO5L 100mg
A13004-50IDO5L 50mg
A13004-10IDO5L 10mg
A13004-500IDO5L 500mg
A13004-25IDO5L 25mg
A13004-5IDO5L 5mg
A13004-1000IDO5L (INCB024360 analog) 1g
A13004-200IDO5L (INCB024360 analog) 200mg
A13004-10mM-DIDO5L 10mM * 1mL in DMSO

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