Etravirine

• Target :

  Reverse Transcriptase|||HIV Protease

• Related Pathways :

  Microbiology/Virology|||Proteases/Proteasome

• Purity :

  0.9974

• Bioactivity :

  Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs. It can bind the enzyme reverse transcriptase (RT) in multiple conformations, both for native and mutant RT, thereby blocking the enzymatic activity of RT.

• Smiles :

  O(C1=NC(NC2=CC=C(C#N)C=C2)=NC(N)=C1Br)C3=C(C)C=C(C#N)C=C3C

• Molecular Formula :

  C20H15BrN6O

• Molecular Weight :

  435.28

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  269055-15-4