Baricitinib

• Target:

  Chk|||JAK|||Tyrosine Kinases

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||JAK/STAT signaling|||Angiogenesis|||Cell Cycle/Checkpoint|||Stem Cells

• Purity:

  >99.99%

• Bioactivity:

  Baricitinib (INCB028050) is a JAK1 and JAK2 inhibitor (IC50=5.9/5.7 nM) with selective and oral activity. Baricitinib has potential anti-inflammatory, immunomodulatory and anti-tumor activity.

• Smiles:

  CCS(=O)(=O)N1CC(CC#N)(C1)n1cc(cn1)-c1[nH]cnc2nccc12

• Molecular Formula:

  C16H17N7O2S

• Molecular Weight:

  371.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1187594-09-7