Dacomitinib

CAT: 0931-MF-0018043-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0018043-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
1110813-31-4
Target
EGFR|||Apoptosis
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling|||Apoptosis
Purity
>99.99%
Bioactivity
Dacomitinib (PF299) (PF299804; PF-00299804) is a highly selective, orally bioavailable small-molecule inhibitor of the HER family of tyrosine kinases with IC50 of 6, 45.7 and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively.
Smiles
COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CCCCC1
Molecular Formula
C24H25ClFN5O2
Molecular Weight
469.94
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Alternative Products

CatalogName
445734-01Dacomitinib
RM-D012205-01Dacomitinib-D10
MBS3612936-01Dacomitinib hydrate
HY-13272R-01Dacomitinib (Standard)
HY-118263-01Dacomitinib (hydrate)
RM-D012242-01Dacomitinib Impurity 42
RM-D012241-01Dacomitinib Impurity 41
RM-D012240-01Dacomitinib Impurity 40
RM-D012237-01Dacomitinib Impurity 37
RM-D012227-01Dacomitinib Impurity 27

Popular Products