RLX

• Target :

  Others|||PI3K|||Akt|||FOXO

• Related Pathways :

  Others|||Apoptosis|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling

• Purity :

  0.9981

• Bioactivity :

  RLX (PD 139530) is a PI3K/Akt/FoxO3a signal inhibitor with anticancer activity against tumour cell lines such as colon cancer, inducing sub-G1 arrest and mitochondrial potential loss, thereby inhibiting tumour growth. RLX also exhibits antitussive and anti-asthmatic activity, reducing eosinophils and total lymphocytes in bronchoalveolar lavage (BAL) fluid, and exhibits toxicity toward A549 cells.

• Smiles :

  O=C1C=2C=CC=CC2N=C3N1CCCCC3

• Molecular Formula :

  C13H14N2O

• Molecular Weight :

  214.26

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  4425-23-4