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RLX

CAT: 0931-T24715-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T24715-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
4425-23-4
Target
Others, PI3K, Akt, FOXO
Related Pathways
Others, Apoptosis, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling
Purity
0.9981
Bioactivity
RLX (PD 139530) is a PI3K/Akt/FoxO3a signal inhibitor with anticancer activity against tumour cell lines such as colon cancer, inducing sub-G1 arrest and mitochondrial potential loss, thereby inhibiting tumour growth. RLX also exhibits antitussive and anti-asthmatic activity, reducing eosinophils and total lymphocytes in bronchoalveolar lavage (BAL) fluid, and exhibits toxicity toward A549 cells.
Smiles
O=C1C=2C=CC=CC2N=C3N1CCCCC3
Molecular Formula
C13H14N2O
Molecular Weight
214.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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