RLX

• Target:

  Others|||PI3K|||Akt|||FOXO

• Related Pathways:

  Others|||Apoptosis|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling

• Purity:

  0.9981

• Bioactivity:

  RLX (PD 139530) is a PI3K/Akt/FoxO3a signal inhibitor with anticancer activity against tumour cell lines such as colon cancer, inducing sub-G1 arrest and mitochondrial potential loss, thereby inhibiting tumour growth. RLX also exhibits antitussive and anti-asthmatic activity, reducing eosinophils and total lymphocytes in bronchoalveolar lavage (BAL) fluid, and exhibits toxicity toward A549 cells.

• Smiles:

  O=C1C=2C=CC=CC2N=C3N1CCCCC3

• Molecular Formula:

  C13H14N2O

• Molecular Weight:

  214.26

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  4425-23-4