PF-06372222

• Target :

  Others|||Glucagon Receptor

• Related Pathways :

  Others|||GPCR/G Protein

• Bioactivity :

  PF-06372222 is a small-molecule negative allosteric modulator of the glucagon receptor (GCGR) . PF-06372222 is also an antagonist for glucagon-like peptide-1 receptor GLP-1R, which inhibits glucagon secretion and glucose-dependent insulin secretion.

• Smiles :

  [C@@H](NC=1C=CC(=NC1)N2C=C(C(F)(F)F)N=C2)(C3CC(C)(C)C3)C4=CC=C(C(NCCC(O)=O)=O)C=C4

• Molecular Formula :

  C26H28F3N5O3

• Molecular Weight :

  515.53

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1407592-99-7