PF-06372222

• Target:

  Others|||Glucagon Receptor

• Related Pathways:

  Others|||GPCR/G Protein

• Bioactivity:

  PF-06372222 is a small-molecule negative allosteric modulator of the glucagon receptor (GCGR) . PF-06372222 is also an antagonist for glucagon-like peptide-1 receptor GLP-1R, which inhibits glucagon secretion and glucose-dependent insulin secretion.

• Smiles:

  [C@@H] (NC=1C=CC (=NC1) N2C=C (C (F) (F) F) N=C2) (C3CC (C) (C) C3) C4=CC=C (C (NCCC (O) =O) =O) C=C4

• Molecular Formula:

  C26H28F3N5O3

• Molecular Weight:

  515.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1407592-99-7