PF-06372222

CAT: 0931-T24620-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T24620-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1407592-99-7
Target
Others|||Glucagon Receptor
Related Pathways
Others|||GPCR/G Protein
Bioactivity
PF-06372222 is a small-molecule negative allosteric modulator of the glucagon receptor (GCGR) . PF-06372222 is also an antagonist for glucagon-like peptide-1 receptor GLP-1R, which inhibits glucagon secretion and glucose-dependent insulin secretion.
Smiles
[C@@H](NC=1C=CC(=NC1)N2C=C(C(F)(F)F)N=C2)(C3CC(C)(C)C3)C4=CC=C(C(NCCC(O)=O)=O)C=C4
Molecular Formula
C26H28F3N5O3
Molecular Weight
515.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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