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PIK-90

CAT: 0931-T2461-02Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T2461-02Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
677338-12-4
Target
DNA-PK, PI3K
Related Pathways
PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair
Purity
0.9989
Bioactivity
PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110α (IC50=11 nM), p110γ (IC50=18 nM) and DNA-PK (IC50=13 nM) .
Smiles
COc1ccc2C3=NCCN3C(NC(=O)c3cccnc3)=Nc2c1OC
Molecular Formula
C18H17N5O3
Molecular Weight
351.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

N-(7,8-dimethoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)nicotinamide

N-(7,8-dimethoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide is a member of quinazolines.

CAS Number677338-12-4
PubChem CID135398491
IUPAC NameN-(7,8-dimethoxy-2,3-dihydro-1H-imidazo[1,2-c]quinazolin-5-ylidene)pyridine-3-carboxamide
Molecular FormulaC18H17N5O3
Molecular Weight351.4
XLogP1.3
Topological Polar Surface Area88.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count26
Formal Charge0
Complexity778
SMILES
COC1=C(C2=NC(=NC(=O)C3=CN=CC=C3)N4CCNC4=C2C=C1)OC
InChI
InChI=1S/C18H17N5O3/c1-25-13-6-5-12-14(15(13)26-2)21-18(23-9-8-20-16(12)23)22-17(24)11-4-3-7-19-10-11/h3-7,10,20H,8-9H2,1-2H3
InChIKey
FCKJZIRDZMVDEM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(7,8-dimethoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)nicotinamide
CAS: 677338-12-4
CID: 135398491
Formula: C18H17N5O3
MW: 351.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight351.4
XLogP31.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass351.13313942
Monoisotopic Mass351.13313942
Topological Polar Surface Area88.4 Ų
Heavy Atom Count26
Formal Charge0
Complexity778
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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