IHR-1

• Target:

  Smo

• Related Pathways:

  Stem Cells

• Purity:

  0.986

• Bioactivity:

  IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM) . Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.

• Smiles:

  Clc1ccc(Cl)c(c1)C(=O)Nc1ccc(NC(=O)c2cc(Cl)ccc2Cl)cc1

• Molecular Formula:

  C20H12Cl4N2O2

• Molecular Weight:

  454.13

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  548779-60-8