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PP121

CAT: 0931-T2415-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T2415-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1092788-83-4
Target
PDGFR, VEGFR, Apoptosis, mTOR, Hck, Src, Bcr-Abl
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling, Angiogenesis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors
Purity
0.9993
Bioactivity
PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2 (IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM), also inhibits DNA-PK (IC50: 60 nM) .
Smiles
Nc1ncnc2n(nc(-c3cnc4[nH]ccc4c3)c12)C1CCCC1
Molecular Formula
C17H17N7
Molecular Weight
319.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
B2172-200PP121
A11207-100PP121 100mg
A11207-25PP121 25mg
A11207-50PP121 50mg

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