Products for Research Use Only

Heclin

CAT: 0931-T24136-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T24136-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
890605-54-6
Target
NEDD4-1, Akt, E1/E2/E3 Enzyme, MyD88
Related Pathways
PI3K/Akt/mTOR signaling, Ubiquitination, Cytoskeletal Signaling, Immunology/Inflammation, Metabolism
Purity
0.9925
Bioactivity
Heclin is an inhibitor of HECT E3 ubiquitin ligase that acts by inhibiting Smurf2, Nedd4, and WWP1 with IC50 values of 6.8, 6.3, and 6.9 μM, respectively.
Smiles
CCc1ccc(\C=C\C(=O)Nc2ccc(cc2)C(C)=O)o1
Molecular Formula
C17H17NO3
Molecular Weight
283.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C