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Nedaplatin

CAT: 0931-T2410-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T2410-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
95734-82-0
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
>99.99%
Bioactivity
Nedaplatin (NSC-375101D) is a derivative of cisplatin and DNA damage agent for tumor colony forming units (IC50: 94 μM) . Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucleophilic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death.
Smiles
N.N.[Pt++].[O-]CC([O-])=O
Molecular Formula
C2H8N2O3Pt
Molecular Weight
303.17
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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