Alogliptin Benzoate

• Target:

  Proteasome|||Ferroptosis|||DPP-4

• Related Pathways:

  Ubiquitination|||Apoptosis|||Proteases/Proteasome

• Purity:

  >99.99%

• Bioactivity:

  Alogliptin Benzoate (SYR 322) (SYR 322), an effective and specific DPP-4 inhibitor (IC50<10 nM), exhibits greater than 10, 000-fold selectivity over DPP-8/9. Alogliptin may inhibit inflammatory responses by preventing the toll-like receptor 4 (TLR-4) -mediated formation of proinflammatory cytokines.

• Smiles:

  Cn1c(=O)cc(n(c1=O)Cc1ccccc1C#N)N1CCC[C@H](C1)N.c1ccc(cc1)C(=O)O

• Molecular Formula:

  C25H27N5O4

• Molecular Weight:

  461.51

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  850649-62-6