Bortezomib

• Target:

  Apoptosis|||NF-?B|||Proteasome|||Autophagy

• Related Pathways:

  Ubiquitination|||NF-?B|||Apoptosis|||Proteases/Proteasome|||Autophagy

• Purity:

  >99.99%

• Bioactivity:

  Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective. Bortezomib has antitumor activity and inhibits NF-?B, which can disrupt the cell cycle and induce apoptosis.

• Smiles:

  CC (C) C[C@H] (NC (=O) [C@H] (Cc1ccccc1) NC (=O) c1cnccn1) B (O) O

• Molecular Formula:

  C19H25BN4O4

• Molecular Weight:

  384.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  179324-69-7