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Bortezomib

CAT: 0931-T2399-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T2399-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
179324-69-7
Target
Apoptosis, NF-κB, Proteasome, Autophagy
Related Pathways
Ubiquitination, NF-κB, Apoptosis, Proteases/Proteasome, Autophagy
Purity
>99.99%
Bioactivity
Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective. Bortezomib has antitumor activity and inhibits NF-κB, which can disrupt the cell cycle and induce apoptosis.
Smiles
CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O
Molecular Formula
C19H25BN4O4
Molecular Weight
384.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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