Bortezomib

• Target :

  Apoptosis|||NF-?B|||Proteasome|||Autophagy

• Related Pathways :

  Ubiquitination|||NF-?B|||Apoptosis|||Proteases/Proteasome|||Autophagy

• Purity :

  >99.99%

• Bioactivity :

  Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective. Bortezomib has antitumor activity and inhibits NF-?B, which can disrupt the cell cycle and induce apoptosis.

• Smiles :

  CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O

• Molecular Formula :

  C19H25BN4O4

• Molecular Weight :

  384.24

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  179324-69-7