Vemurafenib

• Target :

  Autophagy|||Raf|||MAPK|||Src|||ACK1

• Related Pathways :

  Angiogenesis|||Tyrosine Kinase/Adaptors|||MAPK|||Autophagy

• Purity :

  0.9965

• Bioactivity :

  Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently. Vemurafenib exhibits antitumor activity and is used for the treatment of BRAF V600E mutation-positive melanoma.

• Smiles :

  C(=O)(C=1C=2C(NC1)=NC=C(C2)C3=CC=C(Cl)C=C3)C4=C(F)C(NS(CCC)(=O)=O)=CC=C4F

• Molecular Formula :

  C23H18ClF2N3O3S

• Molecular Weight :

  489.92

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  918504-65-1