Vemurafenib

• Target:

  Autophagy|||Raf|||MAPK|||Src|||ACK1

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors|||MAPK|||Autophagy

• Purity:

  0.9965

• Bioactivity:

  Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently. Vemurafenib exhibits antitumor activity and is used for the treatment of BRAF V600E mutation-positive melanoma.

• Smiles:

  C(=O)(C=1C=2C(NC1)=NC=C(C2)C3=CC=C(Cl)C=C3)C4=C(F)C(NS(CCC)(=O)=O)=CC=C4F

• Molecular Formula:

  C23H18ClF2N3O3S

• Molecular Weight:

  489.92

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  918504-65-1