Abemaciclib

• Target :

  CDK

• Related Pathways :

  Cell Cycle/Checkpoint

• Purity :

  0.9987

• Bioactivity :

  Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity. Abemaciclib has antitumor activity and is used to treat advanced or metastatic breast cancer.

• Smiles :

  C(C)(C)N1C=2C(=C(F)C=C(C2)C3=NC(NC4=CC=C(CN5CCN(CC)CC5)C=N4)=NC=C3F)N=C1C

• Molecular Formula :

  C27H32F2N8

• Molecular Weight :

  506.59

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1231929-97-7