Abemaciclib

• Target:

  CDK

• Related Pathways:

  Cell Cycle/Checkpoint

• Purity:

  0.9987

• Bioactivity:

  Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity. Abemaciclib has antitumor activity and is used to treat advanced or metastatic breast cancer.

• Smiles:

  C (C) (C) N1C=2C (=C (F) C=C (C2) C3=NC (NC4=CC=C (CN5CCN (CC) CC5) C=N4) =NC=C3F) N=C1C

• Molecular Formula:

  C27H32F2N8

• Molecular Weight:

  506.59

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1231929-97-7