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ABC1183

CAT: 0931-T23601-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T23601-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1042735-18-1
Target
GSK-3, CDK
Related Pathways
Stem Cells, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint
Purity
0.9892
Bioactivity
ABC1183 is a novel diaminothiazole that inhibits GSK3α, GSK3β and CDK9. ABC1183 inhibits the growth of a numerous cancer cell lines by decreasing cell survival by inducing G2/M arrest and through altering GSK3, glycogen synthetase, β-catenin phosphorylation and MCL1 expression, and is orally active.
Smiles
Cc1ccc(Nc2nc(N)c(s2)C(=O)c2ccc(cc2)C#N)cc1
Molecular Formula
C18H14N4OS
Molecular Weight
334.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-100950RABC1183 (Standard)

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