Neratinib

• Target :

  EGFR|||HER

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling

• Purity :

  >99.99%

• Bioactivity :

  Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.

• Smiles :

  N(C=1C2=C(C=C(OCC)C(NC(/C=C/CN(C)C)=O)=C2)N=CC1C#N)C3=CC(Cl)=C(OCC4=CC=CC=N4)C=C3

• Molecular Formula :

  C30H29ClN6O3

• Molecular Weight :

  557.04

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  698387-09-6