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Icotinib Hydrochloride

CAT: 0931-T2307-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T2307-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1204313-51-8
Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis
Purity
0.9989
Bioactivity
Icotinib Hydrochloride (BPI-2009H) is the hydrochloride salt form of icotinib, an orally available quinazoline-based inhibitor of EGFR, with potential antineoplastic activity. Icotinib selectively inhibits the wild-type and several mutated forms of EGFR tyrosine kinase. This may lead to an inhibition of EGFR-mediated signal transduction and may inhibit cancer cell proliferation. EGFR, a receptor tyrosine kinase, has been upregulated in a variety of cancer cell types.
Smiles
Cl.C#Cc1cccc(Nc2ncnc3cc4OCCOCCOCCOc4cc23)c1
Molecular Formula
C22H22ClN3O4
Molecular Weight
427.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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A3482-5Icotinib Hydrochloride
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