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KL001

CAT: 0931-T22891-08Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0931-T22891-08Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
309928-48-1
Target
Others
Related Pathways
Others
Purity
0.9922
Bioactivity
KL 001 is a Cryptochrome protein (CRY) stabilizer. KL001 prevented ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced gluconeogenesis in primary hepatocytes. KL001 thus provides a tool to study the regulation of CRY-dependent physiology and aid development of clock-based therapeutics of diabetes.
Smiles
CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)Cc1ccco1
Molecular Formula
C21H22N2O4S
Molecular Weight
398.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

KL001

KL001 is an organic molecular entity.

CAS Number309928-48-1
PubChem CID2888648
IUPAC NameN-(3-carbazol-9-yl-2-hydroxypropyl)-N-(furan-2-ylmethyl)methanesulfonamide
Molecular FormulaC21H22N2O4S
Molecular Weight398.5
XLogP2.5
Topological Polar Surface Area84.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Heavy Atom Count28
Formal Charge0
Complexity600
SMILES
CS(=O)(=O)N(CC1=CC=CO1)CC(CN2C3=CC=CC=C3C4=CC=CC=C42)O
InChI
InChI=1S/C21H22N2O4S/c1-28(25,26)22(15-17-7-6-12-27-17)13-16(24)14-23-20-10-4-2-8-18(20)19-9-3-5-11-21(19)23/h2-12,16,24H,13-15H2,1H3
InChIKey
OQAFDLPAPSSOHY-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of KL001
CAS: 309928-48-1
CID: 2888648
Formula: C21H22N2O4S
MW: 398.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight398.5
XLogP32.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Exact Mass398.13002836
Monoisotopic Mass398.13002836
Topological Polar Surface Area84.1 Ų
Heavy Atom Count28
Formal Charge0
Complexity600
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
M13992-01KL001

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