JP1302

CAT: 0931-T22882-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T22882-01Size:1 mg

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CAS Number

80259-18-3

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein, Neuroscience

Purity

0.9996

Bioactivity

JP1302 is a selective α2C adrenoceptor antagonist with a Kb value of 16 nM and a Ki of 28 nM for human α2C receptors.JP1302 has antidepressant activity, disrupts the FACT complex and degrades histone H1.JP1302 has been used in the study of neuropsychiatric disorders, acute renal failure, and renal injury.

Smiles

N(C=1C2=C(N=C3C1C=CC=C3)C=CC=C2)C4=CC=C(C=C4)N5CCN(C)CC5

Molecular Formula

C24H24N4

Molecular Weight

368.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

JP1302

alpha2C-adrenoceptor antagonist, may have therapeutic potential for treatment of neuropsychiatric disorders; structure in first source

CAS Number	80259-18-3
PubChem CID	540335
IUPAC Name	N-[4-(4-methylpiperazin-1-yl)phenyl]acridin-9-amine
Molecular Formula	C24H24N4
Molecular Weight	368.5
XLogP	5
Topological Polar Surface Area	31.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Heavy Atom Count	28
Formal Charge	0
Complexity	473

SMILES

CN1CCN(CC1)C2=CC=C(C=C2)NC3=C4C=CC=CC4=NC5=CC=CC=C53

InChI

InChI=1S/C24H24N4/c1-27-14-16-28(17-15-27)19-12-10-18(11-13-19)25-24-20-6-2-4-8-22(20)26-23-9-5-3-7-21(23)24/h2-13H,14-17H2,1H3,(H,25,26)

InChIKey

QZKGUNQLVFEEBA-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 80259-18-3

CID: 540335

Formula: C24H24N4

MW: 368.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	368.5
XLogP3	5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	368.20009678
Monoisotopic Mass	368.20009678
Topological Polar Surface Area	31.4 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	473
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
T78593-01	JP104

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Catalog	Name
GTR19244174-01	JP1302
HY-103213-01	JP1302 dihydrochloride
HY-103213R-01	JP1302 dihydrochloride (Standard)

JP1302

Chemical Information

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