Bimiralisib

• CAS Number :

  1225037-39-7

• Target :

  MTOR|||PI3K|||S6 Kinase

• Related Pathways :

  MAPK|||PI3K/Akt/mTOR signaling

• Purity :

  0.9988

• Bioactivity :

  Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity. PI3K-IN-2 inhibits the PI3K kinase isoforms alpha, beta, gamma and delta and, to a lesser extent, mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in cells overexpressing PI3K/mTOR. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to both chemotherapy and radiotherapy.

• Smiles :

  Nc1cc(c(cn1)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1)C(F)(F)F

• Molecular Formula :

  C17H20F3N7O2

• Molecular Weight :

  411.38

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C