6-Chloromelatonin

• Target:

  Melatonin Receptor|||Dopamine Receptor

• Related Pathways:

  Neuroscience|||GPCR/G Protein

• Purity:

  0.9936

• Bioactivity:

  6-Chloromelatonin is a potent melatonin receptor agonist, a 5-methoxyindole compound that competes for presynaptic melatonin receptor sites in the rabbit retina, inhibiting the calcium-dependent release of [3H]dopamine with higher metabolic stability than melatonin. Chloromelatonin competitively binds to [3H]melatonin at MT2 receptors (pKi=9.77) and may be used to study insomnia and sleep disorders associated with depression.

• Smiles:

  C (CNC (C) =O) C=1C=2C (=CC (Cl) =C (OC) C2) NC1

• Molecular Formula:

  C13H15ClN2O2

• Molecular Weight:

  266.72

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  63762-74-3