Products for Research Use Only

HKB99

CAT: 0931-T22343Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T22343Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2414908-90-8
Target
ROS, Apoptosis, Phosphatase, Akt, ERK
Related Pathways
MAPK, Metabolism, Apoptosis, Immunology/Inflammation, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling
Purity
0.9735
Bioactivity
HKB99 is a mutant inhibitor of phosphoglycerate mutase 1 (PGAM1), which inhibits the growth and metastasis of non-small cell lung cancer.HKB99 acts synergistically with EGFR inhibitors and assists in the killing of tumors by EGFR inhibitors.HKB99 promotes oxidative stress, which induces alterations in a variety of signaling pathways.HKB99 can be used in the study of metabolism-related diseases.HKB99 can be used in the study of metabolism-related diseases.HKB99 can be used in the study of metabolism-related diseases.
Smiles
O=C1C=2C=CC=CC2C(=O)C3=C(O)C(O)=C(C=C13)NS(=O)(=O)C4=CC=C(C=C4)N5CCC5
Molecular Formula
C23H18N2O6S
Molecular Weight
450.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C