Taletrectinib

• Target:

  ROS|||ROS Kinase|||Trk receptor

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Immunology/Inflammation

• Purity:

  0.9996

• Bioactivity:

  Taletrectinib (AB-106) is a new-generation selective inhibitor of ROS1/NTRK including ROS1, NTRK1, NTRK2 and NTRK3 with IC50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM, respectively.

• Smiles:

  OC(=O)CCCCC(O)=O.C[C@@H](N)COc1ccc(cc1)-c1cnc2ccc(N[C@H](C)c3cccc(F)c3)nn12

• Molecular Formula:

  C29H34FN5O5

• Molecular Weight:

  551.61

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1505515-69-4